Kanehisa Laboratories

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Growth of Sequence and 3D Structure Databases

growth curve

Compiled from:
  1980-1983  Los Alamos sequence analysis system
  1983-1986  IDEAS system at the National Institutes of Health
  1986-1992  IDEAS system at Kyoto University
  1992-      DBGET system in GenomeNet database service

Databases:
  GenBank
  EMBL
  PIR (until 2004.12)
  PRF (until 2010.3)
  SWISS-PROT
  KEGG GENES
  PDB


GenBank

Release Number     Entries        Residues
------------------------------------------
         12/81         263         436,710  Los Alamos Sequence Library
          4/82         315         484,813
          6/82         403         568,083
    1    10/82         440         601,438  GenBank first release by BBN
    2    11/82         540         625,351
    3    12/82         606         680,338
    4     1/83         637         706,596
    5     2/83         705         770,374
    6     3/83       1,093       1,165,783
    7     4/83       1,284       1,321,146
    8     5/83       1,562       1,476,657
    9     6/83       1,773       1,699,705
   10     7/83       1,865       1,827,214
   11     8/83       1,947       1,898,581
   12     9/83       2,222       2,114,326
   13    10/83       2,378       2,217,415
   14    11/83       2,427       2,274,029
   15    12/83       2,562       2,424,475
   16     1/84       3,012       2,602,596
   17     2/84       3,424       2,824,911
   18     3/84       3,521       2,913,629
   19     4/84       3,576       2,945,001
   20     5/84       3,665       3,002,088
   21     6/84       3,825       3,102,728
   22     7/84       3,885       3,126,339
   23     8/84       4,088       3,220,532
   24     9/84       4,135       3,323,270
   25    10/84       4,175       3,368,765
   26    11/84       4,393       3,689,751
   27    12/84       4,526       3,813,396
   28     1/85       4,718       4,024,281
   29     2/85       4,754       4,045,305
   30     3/85       4,878       4,191,115
   31     4/85       4,926       4,257,856
   32     5/85       4,954       4,311,931
   33     6/85       5,001       4,354,111
   34     7/85       5,102       4,449,185
   35     8/85       5,543       5,038,080
   36     9/85       5,700       5,204,420
   37    10/85       5,731       5,248,932
   38    11/85       5,927       5,530,859
   39    12/85       6,044       5,667,645
   40     1/86       6,642       5,925,429
   41     3/86       7,001       6,259,412
   42     5/86       7,416       6,765,476
   43     6/86       8,004       7,416,117
   44     8/86       8,823       8,442,357
   45     9/86       9,411       8,931,101
   46    11/86       9,975       9,594,560
   47    12/86      10,485      10,388,356
   48     2/87      10,913      10,961,365
   49     4/87      11,912      12,209,883
   50     5/87      12,534      13,048,473
   51     6/87      13,619      14,396,626
   52     8/87      14,020      14,855,145
   53     9/87      14,596      15,519,093
   54    12/87      15,465      16,752,872  First release by IntelliGenetics
   55     3/88      17,047      19,156,002
   56     6/88      18,226      20,795,279
   57     9/88      19,044      22,019,698
   58    12/88      21,248      24,690,876
   59     3/89      22,479      26,382,491
   60     6/89      26,317      31,808,784
   61     9/89      28,791      34,762,585
   62    12/89      31,228      37,183,950
   63     3/90      33,377      40,127,752
   64     6/90      35,100      42,495,893
   65     9/90      39,533      49,179,285
   66    12/90      41,057      51,306,092
   67     3/91      43,903      55,169,276
   68     6/91      51,418      65,868,799
   69     9/91      55,631      71,947,426
   70    12/91      58,952      77,337,678
   71     3/92      65,100      83,894,652
   72     6/92      71,280      92,160,761
   73     9/92      78,608     101,008,486
   74    12/92      97,084     120,242,234  GenBank moved to NCBI
   75     2/93     106,684     126,212,259
   76     4/93     111,911     129,968,355
   77     6/93     120,134     138,904,393
   78     8/93     131,328     147,215,633
   79    10/93     143,492     157,152,442
   80    12/93     150,744     163,802,597
   81     2/94     162,946     173,261,500
   82     4/94     169,896     180,589,455
   83     6/94     182,753     191,393,939
   84     8/94     196,703     201,815,802
   85    10/94     215,273     217,102,462
   86    12/94     237,775     230,485,928
   87     2/95     269,478     248,499,214
   88     4/95     352,414     286,094,556
   89     6/95     425,211     318,624,568
   90     8/95     492,483     353,713,490
   91    10/95     555,694     384,939,485
   92    12/95     620,765     425,860,958
   93     2/96     685,693     463,758,833
   94     4/96     744,295     499,127,741
   95     6/96     835,487     551,750,920
   96     8/96     920,588     602,072,354
   97    10/96   1,021,211     651,972,984
   98    12/96   1,114,581     730,552,938
   99     2/97   1,192,505     786,898,138
  100     4/97   1,274,747     842,864,309
  101     6/97   1,491,069     966,993,087
  102     8/97   1,610,848   1,053,474,516
  103    10/97   1,765,847   1,160,300,687
  104    12/97   1,891,953   1,258,290,513
  105     2/98   2,042,325   1,372,368,913
  106     4/98   2,209,232   1,502,542,306
  107     6/98   2,355,928   1,622,041,465
  108     8/98   2,532,359   1,797,137,713
  109    10/98   2,837,897   2,008,761,784
  110    12/98   3,043,729   2,162,067,871
  111     4/99   3,525,418   2,569,578,208
  112     6/99   4,028,171   2,974,791,993
  113     8/99   4,610,118   3,400,237,391
  114    10/99   4,864,570   3,841,163,011
  115    12/99   5,354,511   4,653,932,745
  116     2/00   5,732,757   5,822,145,430
  117     4/00   6,215,002   7,376,080,723
  118     6/00   7,077,491   8,604,221,980
  119     8/00   8,214,339   9,545,724,824
  120    10/00   9,102,634  10,329,057,815
  121    12/00  10,106,023  11,101,066,288
  122     2/01  10,896,781  11,720,120,326
  123     4/01  11,545,572  12,418,544,023
  124     6/01  12,243,766  12,973,707,065
  125     8/01  12,813,516  13,543,364,296
  126    10/01  13,602,262  14,396,883,064
  127    12/01  14,976,310  15,849,921,438
  128     2/02  15,465,325  17,089,143,893       (WGS)
  129     4/02  16,769,983  19,072,679,701     172,768     692,266,338
  130     6/02  17,471,130  20,648,748,345     397,502   3,267,608,441
  131     8/02  18,197,119  22,616,937,182     427,771   3,848,375,582
  132    10/02  19,808,101  26,525,934,656     434,224   3,892,435,593
  133    12/02  22,318,883  28,507,990,166     597,042   6,702,372,564
  134     2/03  23,035,823  29,358,082,791     597,345   6,705,740,844
  135     4/03  24,027,936  31,099,264,455     596,818   6,897,080,355
  136     6/03  25,592,865  32,528,249,295     607,155   6,992,663,962
  137     8/03  27,213,748  33,865,022,251     593,801   7,144,761,762
  138    10/03  29,819,397  35,599,621,471   1,683,437   8,662,242,833
  139    12/03  30,968,418  36,553,368,485   2,547,094  14,523,454,868
  140     2/04  32,549,400  37,893,844,733   3,188,754  22,804,145,885
  141     4/04  33,676,218  38,989,342,565   4,112,532  24,758,556,215
  142     6/04  35,532,003  40,325,321,348   4,353,890  25,592,758,366
  143     8/04  37,343,937  41,808,045,653   4,427,773  28,128,611,847
  144    10/04  38,941,263  43,194,602,655   5,285,276  30,871,590,379
  145    12/04  40,604,319  44,575,745,176   5,410,415  35,009,256,228
  146     2/05  42,734,478  46,849,831,226   6,111,782  38,076,300,084
  147     4/05  44,202,133  48,235,738,567   6,685,746  39,523,208,346
  148     6/05  45,236,251  49,398,852,122   8,711,924  46,767,232,565
  149     8/05  46,947,388  51,674,486,881  10,276,161  53,346,605,784
  150    10/05  49,152,445  53,655,236,500  11,169,448  56,162,807,647
  151    12/05  52,016,762  56,037,734,462  12,088,491  59,638,900,034
  152     2/06  54,584,635  59,750,386,305  12,465,546  63,183,065,091
  153     4/06  56,620,500  61,582,143,971  13,573,144  67,488,612,571
  154     6/06  58,890,345  63,412,609,711  17,733,973  78,858,635,822
  155     8/06  61,132,599  65,369,091,950  17,960,667  80,369,977,826
  156    10/06  62,765,195  66,925,938,907  18,500,772  81,127,502,509
  157    12/06  64,893,747  69,019,290,705  18,540,918  81,611,376,856
  158     2/07  67,218,344  71,292,211,453  19,421,576  86,043,478,524
  159     4/07  71,802,595  75,742,041,056  23,446,831  93,022,691,867
  160     6/07  73,078,143  77,248,690,945  23,718,400  97,102,606,459
  161     8/07  76,146,236  79,525,559,650  25,384,475 101,964,323,738
  162    10/07  77,632,813  81,563,399,765  25,354,041 102,003,045,298
  163    12/07  80,388,382  83,874,179,730  26,177,471 106,505,691,578
  164     2/08  82,853,685  85,759,586,764  27,439,206 108,635,736,141
  165     4/08  85,500,730  89,172,350,468  26,931,049 110,500,961,400
  166     6/08  88,554,578  92,008,611,867  39,163,548 113,639,291,344
  167     8/08  92,748,599  95,033,791,652  40,214,247 118,593,509,342
  168    10/08  96,400,790  97,381,682,336  46,108,952 136,085,973,423
  169    12/08  98,868,465  99,116,431,942  48,394,838 141,374,971,004
  170     2/09 101,815,678 101,467,270,308  49,036,947 143,797,800,446
  171     4/09 103,335,421 102,980,268,709  48,948,309 144,522,542,010
  172     6/09 106,073,709 105,277,306,080  49,063,546 145,959,997,864
  173     8/09 108,431,692 106,533,156,757  48,443,067 148,165,117,763
  174    10/09 110,946,879 108,560,236,506  48,119,301 149,348,923,035
  175    12/09 112,910,950 110,118,557,163  54,076,973 158,317,168,385
  176     2/10 116,461,672 112,326,229,652  57,134,273 163,991,858,015
  177     4/10 119,112,251 114,348,888,771  58,361,599 165,536,009,514
  178     6/10 120,604,423 115,624,497,715  58,592,700 167,725,292,032
  179     8/10 122,941,883 117,476,523,128  58,994,334 169,253,846,128
  180    10/10 125,764,384 118,551,641,086  59,397,637 175,339,059,129
  181    12/10 129,902,276 122,082,812,719  59,608,311 177,385,297,156
  182     2/11 132,015,054 124,277,818,310  62,349,795 190,034,462,797
  183     4/11 135,440,924 126,551,501,141  62,715,288 191,401,393,188
  184     6/11 140,482,268 129,178,292,958  63,735,078 200,487,078,184
  185     8/11 142,284,608 130,671,233,801  64,997,137 208,315,831,132
  186    10/11 144,458,648 132,067,413,372  68,330,215 218,666,368,056
  187    12/11 146,413,798 135,117,731,375  73,729,553 239,868,309,609
  188     2/12 149,819,246 137,384,889,783  78,656,704 261,370,512,675
  189     4/12 151,824,421 139,266,481,398  80,905,298 272,693,351,548
  190     6/12 154,130,210 141,343,240,755  82,076,779 287,577,367,116
  191     8/12 156,424,033 143,081,765,233  84,020,064 308,196,411,905
  192    10/12 157,889,737 145,430,961,262  86,480,509 333,881,846,451
  193    12/12 161,140,325 148,390,863,904  92,767,765 356,002,922,838
  194     2/13 162,886,727 150,141,354,858 103,101,291 390,900,990,416
  195     4/13 164,136,731 151,178,979,155 110,509,314 418,026,593,606
  196     6/13 165,740,164 152,599,230,112 112,488,036 453,829,752,320
  197     8/13 167,295,840 154,192,921,011 124,812,020 500,420,412,665
  198    10/13 168,335,396 155,176,494,699 130,203,205 535,842,167,741
  199    12/13 169,331,407 156,230,531,562 133,818,571 556,764,321,498


EMBL

Release Number     Entries        Residues
------------------------------------------
    1     3/82         568         585,433
    2     4/83         811       1,114,447
    3    12/83       1,481       1,654,854
    4     8/84       1,698       2,147,205
    5     4/85       2,378       2,874,493
    6     8/85       4,835       4,567,592
    7    12/85       5,789       5,622,638
    8     4/86       6,395       6,353,040
    9     9/86       7,630       7,813,214
   10    12/86       8,817       9,766,948
   11     4/87      11,621      12,189,783
   12     7/87      12,706      13,638,061
   13    10/87      14,397      16,023,442
   14     1/88      15,344      17,272,160
   15     5/88      17,961      20,318,442
   16     8/88      19,592      22,625,941
   17    11/88      20,695      24,211,054
   18     2/89      22,938      27,249,830
   19     5/89      24,365      29,066,676
   20     8/89      26,223      31,240,948
   21    11/89      28,679      34,748,087
   22     2/90      31,508      38,165,786
   23     5/90      34,902      42,923,803
   24     8/90      37,784      47,354,438
   25    11/90      41,580      52,900,354
   26     2/91      43,745      55,859,549
   27     5/91      46,871      59,915,244
   28     9/91      54,558      70,448,052
   29    12/91      57,765      75,400,487
   30     2/92      63,378      83,574,342
   31     6/92      72,481      94,390,065
   32     8/92      79,377     101,292,310
   33    12/92      89,100     111,413,979
   34     3/93      99,591     121,420,828
   35     6/93     115,726     139,235,246
   36     9/93     133,252     149,509,542
   37    12/93     154,111     163,353,378
   38     3/94     171,787     179,346,566
   39     6/94     185,883     193,147,264
   40     9/94     212,744     212,015,482
   41    12/94     234,501     227,275,187
   42     3/95     309,892     265,066,849
   43     6/95     422,829     316,126,328
   44     9/95     509,167     363,589,514
   45    12/95     625,746     427,968,276
   46     3/96     704,411     474,040,426
   47     6/96     830,484     551,090,714
   48     8/96     931,582     609,302,252
   49    12/96   1,051,273     696,560,088
   50     3/97   1,191,742     790,157,975
   51     5/97   1,223,674     815,336,041
   52    10/97   1,787,004   1,181,167,498
   53    12/97   1,795,035   1,200,204,361
   54     3/98   2,125,225   1,427,634,373
   55     6/98   2,131,533   1,434,776,497
   56    10/98   2,689,618   1,904,091,473
   57    12/98   3,046,471   2,164,718,256
   58     3/99   3,272,064   2,355,200,790
   59     6/99   3,952,878   2,924,568,545
   60     9/99   4,719,266   3,541,783,272
   61    12/99   5,303,436   4,508,169,737
   62     3/00   5,865,742   6,120,908,677
   63     6/00   6,760,113   8,255,674,441
   64     9/00   8,344,436   9,650,223,037
   65    12/00   9,549,382  10,710,321,435
   66     3/01  11,169,673  11,916,112,872
   67     6/01  12,044,420  12,821,742,622
   68     9/01  12,964,797  13,727,100,206
   69    12/01  14,366,182  14,593,887,845
   70     3/02  15,851,373  17,807,926,047
   71     6/02  17,226,421  20,017,246,707
   72     9/02  18,324,246  22,814,535,107
   73    12/02  20,857,746  27,451,572,799
   74     3/03  23,234,788  29,700,171,231
   75     6/03  25,214,767  32,195,012,823
   76     9/03  27,248,475  33,885,908,155
   77    12/03  30,351,263  36,042,464,651
   78     3/04  32,631,252  37,984,728,579       (WGS)
   79     6/04  34,874,782  39,660,846,601   4,339,341  25,524,702,140
   80     9/04  37,882,872  42,077,895,467   4,429,392  28,144,536,717
   81    12/04  40,696,839  44,285,259,441   5,408,558  34,986,041,399
   82     3/05  43,246,005  46,927,070,905   6,228,397  38,207,643,477
   83     6/05  45,384,527  48,924,454,425   9,107,071  46,071,710,133
   84     9/05  47,652,836  51,954,360,988  11,106,066  55,608,219,735
   85    12/05  52,651,500  56,476,719,034  12,088,383  59,629,958,692
   86     3/06  56,469,697  61,038,435,584  13,313,896  65,362,911,476
   87     6/06  59,344,613  63,468,715,983  14,690,009  71,134,188,512
   88     9/06  62,557,855  66,215,398,674  18,034,036  80,379,878,900
   89    12/06  65,131,214  68,641,747,538  18,535,353  81,521,656,204
   90     3/07  68,733,796  72,366,587,011  18,741,710  87,558,463,507
   91     6/07  73,960,067  77,203,525,567  23,401,573  93,563,351,281
   92     9/07  80,290,768  96,760,235,197  25,405,475 102,118,953,790
   93    12/07  83,340,424 101,041,928,318  26,286,331 106,411,355,062
   94     3/08  87,630,635 105,683,997,481  26,844,416 109,856,555,879
   95     6/08  92,611,994 110,756,150,397  39,159,260 113,595,324,011
   96     9/08  97,703,661 116,529,034,879  40,248,013 118,606,277,503
   97    12/08 103,734,251 120,834,233,638  47,177,340 138,812,922,080
   98     1/09 106,691,156 123,721,885,900  48,422,988 141,585,839,181
   99     3/09 108,942,189 126,361,508,648  49,058,862 143,979,753,892
  100     6/09 112,528,011 129,931,387,893  49,052,170 145,867,524,222
  101     9/09 115,017,081 132,634,993,278  48,639,153 151,113,823,485
  102    12/09 118,457,781 110,076,047,168  49,036,058 156,285,940,473
  103     3/10 122,696,863 112,694,943,984  62,534,503 168,783,808,499
  104     6/10 126,164,806 115,520,667,255  63,955,065 172,425,887,506
  105     9/10 130,856,557 118,061,143,575  64,385,051 174,017,723,116
  106    12/10 134,790,763 121,118,605,096  64,930,106 180,717,164,393
  107     3/11 138,894,159 124,834,070,142  67,677,557 194,855,909,884
  108     6/11 144,622,157 128,994,705,536  68,282,002 197,996,317,514
  109     9/11 149,081,710 131,773,670,586  71,422,297 214,825,028,449
  110    12/11 153,029,172 135,403,508,031  76,992,634 241,068,260,404
  111     3/12 157,289,890 138,690,458,780  84,346,617 272,054,675,882
  112     6/12 160,172,822 141,260,815,522  87,162,867 288,251,573,502
  113     9/12 163,817,932 144,819,967,374  88,288,431 305,661,696,545
  114    12/12 168,376,862 149,154,741,119  97,878,853 350,727,633,526
  115     3/13 171,758,200 151,976,520,628 110,507,391 392,582,439,483
  116     5/13 187,335,482 160,612,039,686 122,178,139 455,636,641,938
  117     9/13 192,953,539 165,469,009,744 131,247,705 504,535,310,634
  118    12/13 196,829,025 168,292,597,695 136,115,247 546,155,476,663


PIR

Release Number    Entries       Residues
----------------------------------------
         10/82      1,993        330,893  NBRF Protein Sequence Database
          2/83      2,145        363,573
          6/83      2,222        387,600
          8/83      2,372        430,262
         11/83      2,509        469,942
          1/84      2,511        470,158
          2/84      2,598        500,581
    1     4/84      2,676        526,466  PIR first release
    2     8/84      2,784        557,759
    3    11/84      2,898        591,717
    4     2/85      3,061        657,289
    5     5/85      3,182        694,014
    6     8/85      3,309        738,997
    7    11/85      3,447        778,218
    8     2/86      3,860        883,800  PIR2 added
    9     5/86      3,993        944,429
   10     8/86      4,248        962,996
   11    12/86      4,612      1,062,149
   12     3/87      4,750      1,103,446
   13     6/87      5,415      1,302,966
   14     9/87      6,418      1,574,608
   15    12/87      6,796      1,684,561
   16     3/88      7,240      1,855,982
   17     6/88      8,588      2,209,397
   18     9/88      9,138      2,377,999
   19    12/88     10,527      2,802,055
   20     3/89     11,158      3,002,182
   21     6/89     12,476      3,406,022
   22     9/89     13,413      3,707,414
   23    12/89     14,372      3,977,903
   24     3/90     16,524      4,627,393
   25     6/90     17,731      4,999,063
   26     9/90     25,814      7,348,950  PIR3 added
   27    12/90     26,798      7,620,668
   28     3/91     28,232      8,076,497
   29     6/91     31,895      9,091,049
   30     9/91     33,989      9,697,617
   31    12/91     36,150     10,360,161
   32     3/92     40,298     11,831,134
   33     6/92     42,215     12,411,076
   34     9/92     44,900     13,205,577
   35    12/92     47,234     13,875,840
   36     3/93     52,257     15,485,766
   37     6/93     56,849     16,691,590
   38     9/93     61,248     18,022,824
   39    12/93     64,760     19,009,044
   40     3/94     67,423     19,747,297
   41     6/94     70,848     20,811,057
   42     9/94     71,995     21,244,777
   43    12/94     75,511     22,468,834
   44     3/95     77,573     23,340,141
   45     6/95     78,488     23,849,247
   46     9/95     82,361     25,276,988
   47    12/95     82,130     25,426,960
   48     3/96     82,182     25,727,516
   49     6/96     84,169     26,719,547
   50     9/96     89,912     28,507,787
   51    12/96     91,006     28,888,923
   52     3/97     92,175     29,420,590
   53     6/97     95,051     30,469,580
   54     9/97     98,250     31,625,275
   55    12/97    105,998     33,852,246
   56     3/98    107,076     34,162,168
   57     6/98    109,075     34,838,376
   58     9/98    116,738     37,483,768
   59    12/98    117,704     37,913,700
   60     3/99    122,810     40,089,044
   61     6/99    130,886     43,065,574
   62     9/99    142,080     47,193,853
   63    12/99    168,808     58,654,532
   64     3/00    178,050     61,909,674
   65     6/00    182,106     63,485,053
   66     9/00    195,891     67,925,498
   67    12/00    198,801     68,747,441
   68     3/01    219,241     76,199,051
   69     6/01    232,624     80,607,033
   70     9/01    250,417     85,926,567
   71    12/01    274,514     93,455,518
   72     4/02    283,175     96,096,690
   73     6/02    283,239     96,144,196
   74     9/02    283,227     96,130,023
   75     1/03    283,268     96,147,517
   76     3/03    283,308     96,164,110
   77     6/03    283,329     96,171,031
   78    10/03    283,366     96,186,963
   79     3/04    283,367     96,187,020
   80    12/04    283,416     96,216,763  PIR final release


PRF

Release Number    Entries       Residues
----------------------------------------
   HE     5/83      1,189        129,350
    P     9/83      2,597        328,302
    S     1/84      3,349        508,268
    T     5/84      3,853        638,579
    U     9/84      4,591        820,929
    V     1/85      5,258        977,841
    W     5/85      6,122      1,160,990
    X     9/85      6,915      1,356,648
    Y     1/86      7,687      1,565,240
    Z     5/86      8,447      1,780,235
    A     9/86      9,123      1,988,548
    B     1/87      9,888      2,196,866
    C     5/87     10,021      2,351,308
    D     9/87     10,738      2,583,047
    F     1/88     11,414      2,812,137
    G     3/88     11,766      2,933,233
    I     6/88     12,825      3,296,592
    K     9/88     14,234      3,777,160
    M     1/89     15,586      4,267,675
    O     5/89     16,969      4,763,710
    R     9/89     18,383      5,247,659
90-01     1/90     20,206      5,944,750
90-05     5/90     22,201      6,674,591
90-09     9/90     24,716      7,596,021
91-01     1/91     26,758      8,360,579
91-05     5/91     28,552      9,026,117
91-09     9/91     30,471      9,707,717
92-01     1/92     33,109     10,701,989
92-05     5/92     35,069     11,438,479
92-09     9/92     37,431     12,338,141
93-01     1/93     39,041     12,942,745
93-03     3/93     40,493     13,450,986
93-05     5/93     41,784     13,933,155
93-07     7/93     43,396     14,540,060
93-09     9/93     45,323     15,229,031
93-11    11/93     47,895     16,163,279
94-01     1/94     49,109     16,615,985
94-03     3/94     50,427     17,115,256
94-05     5/94     52,424     17,878,290
94-07     7/94     54,336     18,618,956
94-09     9/94     55,686     19,113,900
94-11    11/94     57,526     19,781,002
95-03     3/95     60,280     20,878,197
95-05     5/95     61,976     21,586,557
95-07     7/95     64,224     22,462,626
95-09     9/95     66,088     23,199,573
95-11    11/95     68,344     24,039,370
96-05     5/96     73,507     26,117,830
96-07     7/96     75,002     26,744,498
96-09     9/96     76,516     27,346,797
96-11    11/96     78,074     27,986,179
97-01     1/97     80,057     28,814,925
97-03     3/97     81,745     29,523,962
97-05     5/97     83,654     30,172,232
97-07     7/97     85,455     30,915,028
97-09     9/97     87,210     31,626,928
97-11    11/97     89,650     32,564,615
98-01     1/98     92,780     33,698,792
98-03     3/98     98,089     35,346,668
98-05     5/98    101,648     36,591,984
98-07     7/98    103,558     37,415,707
98-09     9/98    108,435     39,113,650
98-11    11/98    110,607     40,088,986
99-01     1/99    112,325     40,777,760
99-03     3/99    114,700     41,714,944
99-05     5/99    116,101     42,247,911
99-07     7/99    118,187     43,138,973
99-09     9/99    121,124     44,331,510
99-11    11/99    127,987     46,538,259
   71     1/00    131,333     47,773,661
   72     3/00    133,212     48,514,385
   75     9/00    141,245     51,691,661
   76    11/00    143,874     52,686,062
   77     1/01    148,099     54,132,882
   78     3/01    156,099     56,871,020
   79     5/01    159,365     58,171,975
   80     7/01    167,028     60,637,099
   81     9/01    177,941     64,250,697
   82    11/01    184,903     66,779,062
   83     1/02    192,393     69,036,232
   84     3/02    195,660     70,303,230
   85     5/02    201,504     72,366,792
   86     7/02    205,029     73,676,338
   87     9/02    210,905     75,522,558
   88    11/02    213,858     76,589,039
   89     1/03    216,752     77,654,078
   90     3/03    225,081     80,471,112
   91     5/03    229,482     81,948,043
   92     7/03    233,109     83,159,165
   93     9/03    236,775     84,291,559
   94    11/03    239,691     85,242,614
   96     3/04    250,321     88,775,826
   97     6/04    256,940     91,047,656
   98     8/04    262,644     93,071,449
   99     9/04    270,439     95,679,062
  101     1/05    308,406    107,781,252
  102     4/05    353,698    122,815,546
  103     6/05    381,094    133,018,204
  104     7/05    422,024    148,104,854
  105     9/05    459,765    164,142,730
  106    11/05    476,919    169,820,614
  108     3/06    555,007    195,757,276
  110     7/06    632,307    218,934,604
  111     9/06    656,550    225,703,601
  113     1/07    773,622    262,958,213
  114     3/07    791,254    268,734,103
  115     5/07    810,251    274,837,576
  116     7/07    832,123    281,306,426
  117     9/07    856,684    288,910,758
  118    11/07    884,108    297,506,754
  119     1/08    898,996    301,975,793
  120     3/08    917,732    308,121,247
  121     5/08    964,264    319,975,640
  122     7/08    985,606    326,208,855
  123     9/08  1,010,213    334,346,452
  124    11/08  1,040,207    343,704,089
  125     1/09  1,058,034    349,200,569
  126     3/09  1,093,029    362,083,599
  127     5/09  1,141,626    377,716,090
  128     7/09  1,202,938    396,565,000
  129     9/09  1,237,647    408,230,417
  130    11/09  1,277,847    421,621,904
  131     1/10  1,326,246    436,826,311
  132     3/10  1,365,912    448,959,615  PRF final release


SWISS-PROT

Release Number    Entries       Residues
----------------------------------------
    2     9/86      3,939        900,163
    3    11/86      4,160        969,641
    4     4/87      4,387      1,036,010
    5     9/87      5,205      1,327,683
    6     1/88      6,102      1,653,982
    7     4/88      6,821      1,885,771
    8     8/88      7,724      2,224,465
    9    11/88      8,702      2,498,140
   10     3/89     10,008      2,952,613
   11     7/89     10,856      3,265,966
   12    10/89     12,305      3,797,482
   13     1/90     13,837      4,347,336
   14     4/90     15,409      4,914,264
   15     8/90     16,941      5,486,399
   16    11/90     18,364      5,986,949
   17     2/91     20,024      6,524,504
   18     5/91     20,772      6,792,034
   19     8/91     21,795      7,173,785
   20    11/91     22,654      7,500,130
   21     3/92     23,742      7,866,596
   22     5/92     25,044      8,375,696
   23     8/92     26,706      9,011,391
   24    12/92     28,154      9,545,427
   25     4/93     29,955     10,214,020
   26     7/93     31,808     10,875,091
   27    10/93     33,329     11,484,420
   28     2/94     36,000     12,496,420
   29     6/94     38,303     13,464,008
   30    10/94     40,292     14,147,368
   31     2/95     43,470     15,335,248
   32    11/95     49,340     17,385,503
   33     2/96     52,205     18,531,385
   34    10/96     59,021     21,210,388
   35    11/97     69,113     25,083,768
   36     7/98     74,019     26,840,295
   37    12/98     77,977     28,268,293
   38     7/99     80,000     29,085,965
   39     5/00     86,593     31,411,157
   40    10/01    101,602     37,315,215
   41     2/03    122,564     44,986,459
   42    10/03    135,850     50,046,799
   43     3/04    146,720     54,093,154
   44     7/04    153,871     56,608,159
   45    10/04    163,235     59,631,787
   46     2/05    168,297     61,443,278
   47     5/05    181,577     65,746,672
   48     9/05    194,317     70,391,852
   49     2/06    207,132     75,438,310
   50     5/06    222,289     81,585,146
   51    10/06    241,242     88,541,632
   52     3/07    261,513     95,638,062
   53     5/07    269,293     98,902,758
   54     7/07    276,256    101,466,206
   55     2/08    356,194    127,836,513
   56     7/08    392,667    141,217,034
   57     3/09    428,650    154,416,236
 2010_06  5/10    517,100    182,146,551
 2010_12 11/10    523,151    184,678,199
 2011_06  5/11    529,056    187,423,367
 2011_12 11/11    533,657    189,261,966
 2012_06  5/12    536,489    190,389,898
 2013_04  4/13    539,829    191,670,831
 2013_12 12/13    541,954    192,668,437


KEGG GENES

Release Number    Entries
----------------------------------------
    7     7/98     65,592
    8    10/98     76,891
    9     1/99     78,337
   10     4/99     97,480
   11     7/99     93,445
   11.1   9/99    107,118
   12    10/99    110,586                         (Genome)
   13     1/00    114,553                            25
   14     4/00    129,057                            30
   15     7/00    138,518                            31
   16    10/00    157,339                            34
   17     1/01    174,226                            39
   18     4/01    203,246                            45
   19     7/01    223,104                            53
   20    10/01    248,705                            60
   21     1/02    328,344                            79
   22     4/02    340,353                            82
   23     7/02    343,860                (KO)        95
   24    10/02    358,597                3,115      101
   25     1/03    417,535                3,371      118
   26     4/03    486,190                3,444      133
   27     7/03    526,464                3,627      145
   28    10/03    580,843    (DGENES)    3,828      163
   29     1/04    597,435    301,883     3,976      174
   30     4/04    659,611    299,559     4,425      190
   31     7/04    713,034    285,449     4,715      205
   32    10/04    772,389    339,558     5,540      220
   33     1/05    866,039    438,613     5,841      233 
   34     4/05    911,578    412,624     6,220      247 
   35     7/05    940,517    597,269     6,674      284 
   36    10/05  1,133,099    597,849     7,499      313 
   37     1/06  1,254,322                7,983      348 
   38     4/06  1,408,931    597,092     8,254      374 
   39     7/06  1,549,332    589,268     8,553      409 
   40    10/06  1,646,611                8,942      436 
   41     1/07  1,871,732                9,286      486 
   42     4/07  2,038,004                9,770      536 
   43     7/07  2,396,769    608,087    10,016      593 
   44    10/07  2,669,491    286,440    10,325      650 
   45     1/08  2,846,561    379,373    10,686      694 
   46     4/08  3,019,823    542,031    10,763      748 
   47     7/08  3,321,599    530,515    10,958      806 
   48    10/08  4,010,399  <= merged    11,208      857 
   49     1/09  4,214,060  <= merged    11,417      899 
   50     4/09  4,229,488    239,041    11,760      957 
   51     7/09  4,604,914    151,662    12,259    1,022 
   52    10/09  4,854,460               12,520    1,088 
   53     1/10  5,195,943    146,715    12,877    1,151 
   54     4/10  5,422,765    232,640    13,369    1,209 
   55     7/10  5,659,677    294,638    13,660    1,263 
   56    10/10  5,818,226               13,820    1,329 
   57     1/11  6,104,532    372,418    14,069    1,390 
   58     4/11  6,375,680               14,387    1,463 
   59     7/11  6,759,505    398,519    14,857    1,573 
   60    10/11  7,107,929    365,986    15,200    1,639 
   61     1/12  7,176,414    356,803    15,400    1,663 
   62     4/12  7,674,147               15,552    1,781 
   63     7/12  8,837,513               15,728    2,168 
   64    10/12  9,113,391    335,886    15,950    2,262
   65     1/13  9,794,752               16,282    2,407
   66     4/13 10,211,206    288,761    16,485    2,535
   67     7/13 10,909,953    432,488    16,791    2,720
   68    10/13 11,509,872    417,865    17,172    2,867
   69     1/14 12,216,183    442,323    17,399    2,986


PDB

Release Number    Entries
----------------------------------------
    5    11/77         84
    6     5/78         96
    7    12/78        112
    8     4/79        123
    9     7/79        126
   10    10/79        134
   13     7/80        146
   14    10/80        151
   15     1/81        153
   16     4/81        159
   17     7/81        167
   18    10/81        172
   19     1/82        172
   20     4/82        190
   21     7/82        210
   22    10/82        215
   23     1/83        220
   24     4/83        224
   25     7/83        230
   26    10/83        234
   27     1/84        243
   28     4/84        237
   29     7/84        252
   30    10/84        254
   31     1/85        264
   32     4/85        270
   33     7/85        273
   34    10/85        279
   35     1/86        286
   36     4/86        288
   37     7/86        294
   38    10/86        296
   39     1/87        301
   40     4/87        307
   41     7/87        310
   42    10/87        318
   43     1/88        328
   44     4/88        354
   45     7/88        368
   46    10/88        381
   47     1/89        413
   48     4/89        427
   49     7/89        435
   50    10/89        459
   51     1/90        503
   52     4/90        535
   53     7/90        554
   54    10/90        597
   55     1/91        622
   56     4/91        655
   57     7/91        688
   58    10/91        790
   59     1/92        851
   60     4/92      1,005
   61     7/92      1,146
   62    10/92      1,307
   63     1/93      1,492
   64     4/93      1,666
   65     7/93        ??? (not distributed)
   66    10/93      2,049
   67     1/94      2,327
   68     4/94      2,440
   69     7/94      2,684
   70    10/94      2,921        901,772
   71     1/95      3,091        926,235
   72     4/95      3,528      1,069,045
   73     7/95      3,765      1,144,986
   74    10/95      3,897      1,191,278
   75     1/96      4,238      1,317,176
   76     4/96      4,508      1,403,823
   77     7/96      4,728      1,479,089
   78    10/96      4,949      1,552,150
   79     1/97      5,478      1,756,248
   80     4/97      5,887      1,912,201
   81     7/97      6,173      2,023,537
   82    10/97      6,567      2,207,715
   83     1/98      7,023      2,417,274
   84     4/98      7,533      2,644,523
   85     7/98      8,035
   86    10/98      8,492      3,158,591
    1     3/99      9,176                 PDB moved to RCSB
    2     6/99      9,631
    3     9/99     10,213
    4    12/99     11,317
    5     4/00     12,110
    6     7/00     12,592
    7    10/00     13,270
    8     1/01     14,040
    9     4/01     14,731
   10     7/01     15,488
   11    10/01     16,121
   12     1/02     16,972
   13     4/02     17,737
   14     7/02     18,528
   15    10/02     18,838
   16     1/03     19,623
   17     4/03     20,533
   18     6/03     21,248
   19    10/03     22,700
   20     1/04     23,792
   21     4/04     24,908
   22     7/04     26,144
   23    10/04     27,428
   24     1/05     28,992
   25     4/05     30,263
   26     7/05     31,535
   27    10/05     32,823
   28     1/06     34,376
   29     4/06     35,813
   30     7/06     37,392
   31    10/06     39,051
   32     1/07     40,933
   33     4/07     42,474
   34     7/07     44,320
   35    10/07     46,051
   36     1/08     48,091
   37     4/08     49,760
   38     7/08     51,491
   39    10/08     53,384
   40     1/09     55,072
   41     4/09     56,751
   42     7/09     58,588
   43    10/09     60,464
   44     1/10     62,388
   45     4/10     64,357
   46     7/10     66,212
   47    10/10     68,288
   48     1/11     70,231
   49     4/11     72,104
   50     7/11     74,140
   51    10/11     76,132
   52     1/12     78,237
   53     4/12     80,402
   54     7/12     82,679
   55    10/12     84,846
   56     1/13     87,153
   57     4/13     89,212
   58     7/13     91,761
   59    10/13     94,143


Text last updated: January 1, 2014
Figure last updated: September 16, 2013

Kanehisa Laboratories NPO Bioinformatics Japan Pathway Solutions