Integration of Minimum Evolution and Maximum Likelihood Method in Constructing Molecular Evolutionary Tree

Hiroshi Tanaka (
Fengrong Ren (
Norio Fukuda (

Tokyo Medical and Dental University
Yushima 1-5-45, Bunkyo 113, Japan


The maximum likelihood method and minimum evolution method are mainly used to reconstruct the molecular evolutionary phylogenetic trees. But, from statistical viewpoints, each of them has its own problem. To improve this, we combine the maximum likelihood method with minimum evolution method, on the framework of Bayesian maximum a posterior probability(MAP) estimation.