Sequence Motif Analysis and Retrieval Tool

Atsushi Ogiwara (
Ikuo Uchiyama (
Minoru Kanehisa (

Institute for Chemical Research
Kyoto University
Uji, Kyoto 611, Japan


The Sequence Motif Analysis and Retrieval Tool (SMART) is a computer program package that searches sequence motifs in a query protein sequence and gives additional information of structural and functional features about the detected motifs. These features are represented in a graphical fashion, and for structural features, users can manipulate the three-dimensional structures containing the detected motifs using a graphical user interface. SMART aims at providing more useful information for interpreting biological functions of the query sequence than a simple database retrieval of homology searches. SMART works on Sun workstations with an X windows graphical user interface system.