Highly parallel experimental biology is offering opportunities to not just accomplish work more easily, but to explore for underlying governing principles.&&Recent analysis of the large-scale organization of gene expression has revealed its complex and dynamic nature.&&However, the underlying dynamics that generate complex gene expression and cellular organization are not yet understood.&&To comprehensively and quantitatively elucidate these underlying gene expression dynamics, we have analyzed genome-wide gene expression in many experimental conditions in Escherichia coli, Saccharomyces cerevisiae, Arabidopsis thaliana, Drosophila melanogaster, Mus musculus and Homo sapiens.&&Here we demonstrate that the gene expression dynamics follows the same and surprisingly simple principle from Escherichia coli to man; where gene expression changes are proportional to their expression levels, and show that this 'proportional' dynamics or 'rich-travel-more' mechanism can regenerate the observed complex and dynamic organization of the transcriptome. These findings provide a universal principle in the regulation of gene expression, show how complex and dynamic organization can emerge from simple underlying dynamics, and demonstrate the flexibility of transcription across a< wide range of expression levels.&&We will also discuss about the "rich-travel-more" mechanism in the evolution of heterogeneous organization of metabolic networks.